At Novartis Institutes for BioMedical Research (NIBR), the global research organization of Novartis, we are committed to discovering innovative medicines to cure disease and improve human health.We aim to hire the best trained scientists from academia and biotechnology and pharmaceutical companies, and we cultivate an environment for drug discovery science where innovation is rewarded.It is ultimately the talent of the individuals we recruit that determines our success and our state-of-the-art technologies and resources that enable individuals to realize this success.NIBR conducts research globally with sites in Emeryville, California; Cambridge, MA; East Hanover, NJ; Basel, Switzerland; and Shanghai, China.Our Emeryville location focuses on drug discovery and early development for Infectious Diseases and is actively recruiting for a variety of positions across disciplines such as Bacteriology, Virology, Chemistry, and other areas that support our scientific discovery.

About the Infectious Diseases Area Antibacterial Lead Discovery Group:
The Infectious Diseases Area (IDA) seeks to discover and develop treatments to address unmet medical needs in the management and cure of bacterial and viral infections. The Antibacterial Lead Discovery group in Emeryville is part of the multidisciplinary effort aimed at the discovery of small molecule drugs for the treatment of patients with bacterial diseases. We develop and implement phenotypic and target-based assays aimed at discovering novel agents for antibacterial therapy.

About the position:
We are seeking a motivated individual with a strong scientific background and relevant expertise in the screening of small molecules and mechanistic characterization of novel chemical entities. The successful candidate will have demonstrated competency in developing innovative cell-based and target-based assay technologies as part of lead discovery and lead optimization processes. The candidate will be responsible for the robust execution of assays and interpretation of the resulting data to enable programs to reach decision points. The selected candidate must have excellent written and verbal communication skills.

The responsibilities include (but are not limited to):

Independently perform and interpret cell-based and biochemical screening assays to support drug discovery efforts Independently design, troubleshoot and implement new mechanism of action assays Ensure integrity, quality, and delivery of data in a timely manner Contribute to hypothesis generation, experimental design and interpretation of data.Written and electronic documentation of methods and results Written and oral communication of results to key stakeholders B.S.or M.S.in microbiology, biochemistry or related discipline, with at least 3 years of experience in a pharmaceutical or biotechnology drug discovery environment Proficiencies in mammalian cell culture and assay development are required.Experience with small molecule assay development, lead discovery, and lead optimization in a pharmaceutical setting is preferred.Demonstrated ability to critically evaluate and achieve assay robustness, reproducibility, and data quality Experience with basic workstation laboratory instrumentation and automation (e.g.

Agilent, Biomek, Tecan) and sample management procedures.Strong written and verbal communication skills Able to work independently in a fast-paced environment Qualified candidates will have a commitment to scientific excellence, an appreciation for multidisciplinary technology integration, and an ability to troubleshoot and solve problems.The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment.We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.

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